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Extending long-range phasing and haplotype library imputation algorithms to large and heterogeneous datasets
BACKGROUND: We describe the latest improvements to the long-range phasing (LRP) and haplotype library imputation (HLI) algorithms for successful phasing of both datasets with one million individuals and datasets genotyped using different sets of single nucleotide polymorphisms (SNPs). Previous publi...
Autores principales: | Money, Daniel, Wilson, David, Jenko, Janez, Whalen, Andrew, Thorn, Steve, Gorjanc, Gregor, Hickey, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346379/ https://www.ncbi.nlm.nih.gov/pubmed/32640985 http://dx.doi.org/10.1186/s12711-020-00558-2 |
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