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Generate-Boost: study protocol for a prospective, multicenter, randomized controlled, double-blinded phase II trial to evaluate efficacy and safety of bortezomib in patients with severe autoimmune encephalitis
BACKGROUND: Autoimmune encephalitis is a new spectrum of autoimmune disorders of the central nervous system (CNS), which are characterized by pathogenic autoantibodies against neuronal surface antigens. Clinical presentations range from acute to subacute encephalopathy with neurological and psychiat...
Autores principales: | Wickel, Jonathan, Chung, Ha-Yeun, Platzer, Stephanie, Lehmann, Thomas, Prüss, Harald, Leypoldt, Frank, Günther, Albrecht, Scherag, André, Geis, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346383/ https://www.ncbi.nlm.nih.gov/pubmed/32641101 http://dx.doi.org/10.1186/s13063-020-04516-7 |
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