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The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds
BACKGROUND: Brain aging is a major risk factor in the progression of cognitive diseases including Alzheimer’s disease (AD) and vascular dementia. We investigated a mouse model of brain aging up to 24 months old (mo). METHODS: A high field (11.7T) MRI protocol was developed to characterize specific f...
Autores principales: | Taylor, Erik N., Huang, Nasi, Wisco, Jonathan, Wang, Yandan, Morgan, Kathleen G., Hamilton, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346388/ https://www.ncbi.nlm.nih.gov/pubmed/32641073 http://dx.doi.org/10.1186/s12967-020-02441-6 |
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