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HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies
BACKGROUND: Well-characterized biomaterials of high quality have great potential for acceleration and quality improvement in translational biomedical research. To improve accessibility of local sample collections, efforts have been made to create central biomaterial banks and catalogues. Available t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346399/ https://www.ncbi.nlm.nih.gov/pubmed/32640981 http://dx.doi.org/10.1186/s12859-020-03596-1 |
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author | Heinen, Stephanie Schulze, Nick Franke, Bernd Klein, Florian Lehmann, Clara Vehreschild, Maria J. G. T. Gloistein, Claas Stecher, Melanie Vehreschild, Jörg Janne |
author_facet | Heinen, Stephanie Schulze, Nick Franke, Bernd Klein, Florian Lehmann, Clara Vehreschild, Maria J. G. T. Gloistein, Claas Stecher, Melanie Vehreschild, Jörg Janne |
author_sort | Heinen, Stephanie |
collection | PubMed |
description | BACKGROUND: Well-characterized biomaterials of high quality have great potential for acceleration and quality improvement in translational biomedical research. To improve accessibility of local sample collections, efforts have been made to create central biomaterial banks and catalogues. Available technical solutions for creating professional local sample catalogues and connecting them to central systems are cost intensive and/or technically complex to implement. Therefore, the Translational Thematic Unit HIV of the German Center for Infection Research (DZIF) developed a Laboratory Information and Management System (LIMS) called HIV Engaged Research Technology (HEnRY) for implementation into the Translational Platform HIV (TP-HIV) at the DZIF and other research networks. RESULTS: monitoring of stored samples and associated information; data selection via query tools or Structured Query Language (SQL); preparation of summary documents, including scannable search lists; centralized management of the practical laboratory part of multicentre studies (e.g. import of drawing schemes and sample processing steps), preparation of aliquot shipments, including associated documents to be added to shipments; unique and secure identification of aliquots through use of customizable Quick Response (QR) code labels directly from HEnRY; support of aliquot data transmission to central registries. In summary, HEnRY offers all features necessary for a LIMS software. In addition, the structure of HEnRY provides sufficient flexibility to allow the implementation in other research areas. CONCLUSION: HEnRY is a free biobanking tool published under the MIT license. While it was developed to support HIV research in Germany, the feature set and language options, allow much broader applications and make this a powerful free research tool. |
format | Online Article Text |
id | pubmed-7346399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-73463992020-07-14 HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies Heinen, Stephanie Schulze, Nick Franke, Bernd Klein, Florian Lehmann, Clara Vehreschild, Maria J. G. T. Gloistein, Claas Stecher, Melanie Vehreschild, Jörg Janne BMC Bioinformatics Software BACKGROUND: Well-characterized biomaterials of high quality have great potential for acceleration and quality improvement in translational biomedical research. To improve accessibility of local sample collections, efforts have been made to create central biomaterial banks and catalogues. Available technical solutions for creating professional local sample catalogues and connecting them to central systems are cost intensive and/or technically complex to implement. Therefore, the Translational Thematic Unit HIV of the German Center for Infection Research (DZIF) developed a Laboratory Information and Management System (LIMS) called HIV Engaged Research Technology (HEnRY) for implementation into the Translational Platform HIV (TP-HIV) at the DZIF and other research networks. RESULTS: monitoring of stored samples and associated information; data selection via query tools or Structured Query Language (SQL); preparation of summary documents, including scannable search lists; centralized management of the practical laboratory part of multicentre studies (e.g. import of drawing schemes and sample processing steps), preparation of aliquot shipments, including associated documents to be added to shipments; unique and secure identification of aliquots through use of customizable Quick Response (QR) code labels directly from HEnRY; support of aliquot data transmission to central registries. In summary, HEnRY offers all features necessary for a LIMS software. In addition, the structure of HEnRY provides sufficient flexibility to allow the implementation in other research areas. CONCLUSION: HEnRY is a free biobanking tool published under the MIT license. While it was developed to support HIV research in Germany, the feature set and language options, allow much broader applications and make this a powerful free research tool. BioMed Central 2020-07-08 /pmc/articles/PMC7346399/ /pubmed/32640981 http://dx.doi.org/10.1186/s12859-020-03596-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Software Heinen, Stephanie Schulze, Nick Franke, Bernd Klein, Florian Lehmann, Clara Vehreschild, Maria J. G. T. Gloistein, Claas Stecher, Melanie Vehreschild, Jörg Janne HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title | HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title_full | HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title_fullStr | HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title_full_unstemmed | HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title_short | HEnRY: a DZIF LIMS tool for the collection and documentation of biomaterials in multicentre studies |
title_sort | henry: a dzif lims tool for the collection and documentation of biomaterials in multicentre studies |
topic | Software |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346399/ https://www.ncbi.nlm.nih.gov/pubmed/32640981 http://dx.doi.org/10.1186/s12859-020-03596-1 |
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