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Changes of plasma cGP/IGF‐1 molar ratio with age is associated with cognitive status of Parkinson disease

OBJECTIVE: Cognitive impairment is a common feature of Parkinson disease (PD), for which age is a major contributing factor. Insulin‐like growth factor‐1 (IGF‐1) declines with age and contributes to age‐related cognitive impairment in PD. Cyclic glycine‐proline (cGP) is a metabolite of IGF‐1 and nor...

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Detalles Bibliográficos
Autores principales:	Fan, Dawei, Pitcher, Toni, Dalrymple‐Alford, John, MacAskill, Michael, Anderson, Tim, Guan, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Blood‐based Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346731/ https://www.ncbi.nlm.nih.gov/pubmed/32671179 http://dx.doi.org/10.1002/dad2.12025

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