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Blood DNA methylation signatures to detect dementia prior to overt clinical symptoms

INTRODUCTION: This study determined whether blood DNA methylation (DNAm) patterns differentiate individuals with presymptomatic dementia compared to controls. METHODS: DNAm was measured in 73 individuals prior to dementia diagnosis and 87 cognitively healthy controls matched for age, sex, smoking, e...

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Detalles Bibliográficos
Autores principales:	Fransquet, Peter Daniel, Lacaze, Paul, Saffery, Richard, Phung, James, Parker, Emily, Shah, Raj, Murray, Anne, Woods, Robyn L., Ryan, Joanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Blood‐based Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346866/ https://www.ncbi.nlm.nih.gov/pubmed/32671182 http://dx.doi.org/10.1002/dad2.12056

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