Identification of Disease-associated Traits and Clonotypes in the T Cell Receptor Repertoire of Monozygotic Twins Affected by Inflammatory Bowel Diseases

BACKGROUND AND AIMS: Intestinal inflammation in inflammatory bowel diseases [IBD] is thought to be T cell mediated and therefore dependent on the interaction between the T cell receptor [TCR] and human leukocyte antigen [HLA] proteins expressed on antigen presenting cells. The collection of all TCRs...

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Detalles Bibliográficos
Autores principales: Rosati, Elisa, Pogorelyy, Mikhail V, Dowds, C Marie, Moller, Frederik T, Sorensen, Signe B, Lebedev, Yuri B, Frey, Norbert, Schreiber, Stefan, Spehlmann, Martina E, Andersen, Vibeke, Mamedov, Ilgar Z, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346890/
https://www.ncbi.nlm.nih.gov/pubmed/31711184
http://dx.doi.org/10.1093/ecco-jcc/jjz179

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