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Cerebral venous sinus thrombosis–A primer for emergency physician

Cerebral venous sinus thrombosis (CVT) is notoriously known for its varied presentations and extremely high risk of mortality, if remains undetected and untreated. On the other hand, life can be saved with full functional recovery if CVT can be identified with high index of clinical suspicion with s...

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Autores principales: Chatterjee, Subhankar, Sharma, Chandra Bhushan, Guria, Rishi Tuhin, Dubey, Souvik, J.Lavie, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346905/
https://www.ncbi.nlm.nih.gov/pubmed/32670974
http://dx.doi.org/10.4103/jfmpc.jfmpc_192_20
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author Chatterjee, Subhankar
Sharma, Chandra Bhushan
Guria, Rishi Tuhin
Dubey, Souvik
J.Lavie, Carl
author_facet Chatterjee, Subhankar
Sharma, Chandra Bhushan
Guria, Rishi Tuhin
Dubey, Souvik
J.Lavie, Carl
author_sort Chatterjee, Subhankar
collection PubMed
description Cerebral venous sinus thrombosis (CVT) is notoriously known for its varied presentations and extremely high risk of mortality, if remains undetected and untreated. On the other hand, life can be saved with full functional recovery if CVT can be identified with high index of clinical suspicion with supportive imaging and treatment with appropriate anticoagulation. It is important for clinicians to be meticulous to screen for both the potential reversible and heritable causes of CVT so that appropriate measures can be taken to prevent such catastrophe. Here we report a case of CVT involving right sigmoid and transverse sinuses presenting with acute onset left sided hemiplegic without antecedent headache or seizures. Patient was successfully treated with anticoagulants with nearly full functional recovery. Multiple predisposing factors were identified. As per our knowledge, this is the first case of CVT with underlying conglomeration of multiple acquired (lactation, folate deficiency, hyperhomocysteinemia, depot medroxyprogesterone acetate injection) and hereditary risk factors (deficiency of protein C, protein S and antithrombin-III) in a single patient.
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spelling pubmed-73469052020-07-14 Cerebral venous sinus thrombosis–A primer for emergency physician Chatterjee, Subhankar Sharma, Chandra Bhushan Guria, Rishi Tuhin Dubey, Souvik J.Lavie, Carl J Family Med Prim Care Case Report Cerebral venous sinus thrombosis (CVT) is notoriously known for its varied presentations and extremely high risk of mortality, if remains undetected and untreated. On the other hand, life can be saved with full functional recovery if CVT can be identified with high index of clinical suspicion with supportive imaging and treatment with appropriate anticoagulation. It is important for clinicians to be meticulous to screen for both the potential reversible and heritable causes of CVT so that appropriate measures can be taken to prevent such catastrophe. Here we report a case of CVT involving right sigmoid and transverse sinuses presenting with acute onset left sided hemiplegic without antecedent headache or seizures. Patient was successfully treated with anticoagulants with nearly full functional recovery. Multiple predisposing factors were identified. As per our knowledge, this is the first case of CVT with underlying conglomeration of multiple acquired (lactation, folate deficiency, hyperhomocysteinemia, depot medroxyprogesterone acetate injection) and hereditary risk factors (deficiency of protein C, protein S and antithrombin-III) in a single patient. Wolters Kluwer - Medknow 2020-04-30 /pmc/articles/PMC7346905/ /pubmed/32670974 http://dx.doi.org/10.4103/jfmpc.jfmpc_192_20 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chatterjee, Subhankar
Sharma, Chandra Bhushan
Guria, Rishi Tuhin
Dubey, Souvik
J.Lavie, Carl
Cerebral venous sinus thrombosis–A primer for emergency physician
title Cerebral venous sinus thrombosis–A primer for emergency physician
title_full Cerebral venous sinus thrombosis–A primer for emergency physician
title_fullStr Cerebral venous sinus thrombosis–A primer for emergency physician
title_full_unstemmed Cerebral venous sinus thrombosis–A primer for emergency physician
title_short Cerebral venous sinus thrombosis–A primer for emergency physician
title_sort cerebral venous sinus thrombosis–a primer for emergency physician
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346905/
https://www.ncbi.nlm.nih.gov/pubmed/32670974
http://dx.doi.org/10.4103/jfmpc.jfmpc_192_20
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