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Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17

CONTEXT: During ongoing passive surveillance in Burail, Chandigarh an unexpected rise in number of acute viral hepatitis (AVH) was reported during December 2016. AIMS: An outbreak of AVH was investigated in an urbanized village, Burail, in Chandigarh, India with an objective of describing its epidem...

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Autores principales: Kankaria, Ankita, Gupta, Madhu, Bashar, MD Abu, Aggarwal, Shuchi, Murugan, Sathiabalan, Bhag, Chering, Kumar, Sunil, Chaudhary, Krishna, Sandha, Kawaljeet S., Jain, Ruby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346961/
https://www.ncbi.nlm.nih.gov/pubmed/32670931
http://dx.doi.org/10.4103/jfmpc.jfmpc_1244_19
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author Kankaria, Ankita
Gupta, Madhu
Bashar, MD Abu
Aggarwal, Shuchi
Murugan, Sathiabalan
Bhag, Chering
Kumar, Sunil
Chaudhary, Krishna
Sandha, Kawaljeet S.
Jain, Ruby
author_facet Kankaria, Ankita
Gupta, Madhu
Bashar, MD Abu
Aggarwal, Shuchi
Murugan, Sathiabalan
Bhag, Chering
Kumar, Sunil
Chaudhary, Krishna
Sandha, Kawaljeet S.
Jain, Ruby
author_sort Kankaria, Ankita
collection PubMed
description CONTEXT: During ongoing passive surveillance in Burail, Chandigarh an unexpected rise in number of acute viral hepatitis (AVH) was reported during December 2016. AIMS: An outbreak of AVH was investigated in an urbanized village, Burail, in Chandigarh, India with an objective of describing its epidemiological features. SETTINGS AND DESIGN: A house-to-house survey was conducted in Burail (population 51,958). SUBJECTS AND METHODS: WHO's standard case definition for AVH was used to identify cases. Suspected cases were tested for hepatitis A virus (HAV) and E virus (HEV) using enzyme-linked immunosorbent assay. Drinking water samples were tested for fecal contamination. Control measures were implemented to contain the outbreak. STATISTICAL ANALYSIS USED: Descriptive analysis was done as per time, person, and place. RESULTS: Out of 141 confirmed cases of AVH, 85.1% were positive for HEV, 12.8% for HAV, and 2.1% for both HAV and HEV. The attack rate was 27.1 per 10,000 in a population. Males were affected more than females (P < 0.05). One of the areas reported a leakage in drinking water pipeline and had highest attack rate (36.8/10000 population). Drinking water samples were found negative for contamination. Around 27% of confirmed cases reported history of taking food from local vendors in Burail 2–6 weeks prior to the onset of symptoms. CONCLUSION: This study described the epidemiological features of dual hepatitis outbreak due to HAV and HEV from Chandigarh, Union Territory, north India.
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spelling pubmed-73469612020-07-14 Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17 Kankaria, Ankita Gupta, Madhu Bashar, MD Abu Aggarwal, Shuchi Murugan, Sathiabalan Bhag, Chering Kumar, Sunil Chaudhary, Krishna Sandha, Kawaljeet S. Jain, Ruby J Family Med Prim Care Original Article CONTEXT: During ongoing passive surveillance in Burail, Chandigarh an unexpected rise in number of acute viral hepatitis (AVH) was reported during December 2016. AIMS: An outbreak of AVH was investigated in an urbanized village, Burail, in Chandigarh, India with an objective of describing its epidemiological features. SETTINGS AND DESIGN: A house-to-house survey was conducted in Burail (population 51,958). SUBJECTS AND METHODS: WHO's standard case definition for AVH was used to identify cases. Suspected cases were tested for hepatitis A virus (HAV) and E virus (HEV) using enzyme-linked immunosorbent assay. Drinking water samples were tested for fecal contamination. Control measures were implemented to contain the outbreak. STATISTICAL ANALYSIS USED: Descriptive analysis was done as per time, person, and place. RESULTS: Out of 141 confirmed cases of AVH, 85.1% were positive for HEV, 12.8% for HAV, and 2.1% for both HAV and HEV. The attack rate was 27.1 per 10,000 in a population. Males were affected more than females (P < 0.05). One of the areas reported a leakage in drinking water pipeline and had highest attack rate (36.8/10000 population). Drinking water samples were found negative for contamination. Around 27% of confirmed cases reported history of taking food from local vendors in Burail 2–6 weeks prior to the onset of symptoms. CONCLUSION: This study described the epidemiological features of dual hepatitis outbreak due to HAV and HEV from Chandigarh, Union Territory, north India. Wolters Kluwer - Medknow 2020-04-30 /pmc/articles/PMC7346961/ /pubmed/32670931 http://dx.doi.org/10.4103/jfmpc.jfmpc_1244_19 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kankaria, Ankita
Gupta, Madhu
Bashar, MD Abu
Aggarwal, Shuchi
Murugan, Sathiabalan
Bhag, Chering
Kumar, Sunil
Chaudhary, Krishna
Sandha, Kawaljeet S.
Jain, Ruby
Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title_full Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title_fullStr Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title_full_unstemmed Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title_short Epidemiological investigation of an outbreak of Acute Viral Hepatitis A and E in a semi-urban locality in Chandigarh, North Indian Union Territory, 2016–17
title_sort epidemiological investigation of an outbreak of acute viral hepatitis a and e in a semi-urban locality in chandigarh, north indian union territory, 2016–17
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346961/
https://www.ncbi.nlm.nih.gov/pubmed/32670931
http://dx.doi.org/10.4103/jfmpc.jfmpc_1244_19
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