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Amitraz poisoning: Early gastric lavage can prevent life-threatening complications

Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects...

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Detalles Bibliográficos
Autores principales: Madhuri, Pratti, Mukherjee, Anirudh, Manna, Sukdev, Dhar, Minakshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346969/
https://www.ncbi.nlm.nih.gov/pubmed/32670980
http://dx.doi.org/10.4103/jfmpc.jfmpc_1268_19
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author Madhuri, Pratti
Mukherjee, Anirudh
Manna, Sukdev
Dhar, Minakshi
author_facet Madhuri, Pratti
Mukherjee, Anirudh
Manna, Sukdev
Dhar, Minakshi
author_sort Madhuri, Pratti
collection PubMed
description Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening. Because of lack of specific antidote patients are usually managed with supportive and symptomatic management. We describe a case of 36-year-old female patient who presented to us with alleged history of 120 ml amitraz ingestion. She was given early gastric lavage with activated charcoal at emergency along with supportive and symptomatic management. She developed mild CNS depression, bradycardia, miosis, and fluctuating blood pressure. She was managed in intensive care unit and was kept under close hemodynamic monitoring. Her clinical course during hospital stay was uneventful and was successfully discharged without any residual deficits. According to previously published data, this amount of amitraz intoxication could have caused more serious clinical manifestations. This disproportionately less severe clinical manifestation in our patient is attributed to early gastric lavage. Ominous of reducing amitraz-related health hazards lies in the hands of primary health care physicians and regulatory bodies of government.
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spelling pubmed-73469692020-07-14 Amitraz poisoning: Early gastric lavage can prevent life-threatening complications Madhuri, Pratti Mukherjee, Anirudh Manna, Sukdev Dhar, Minakshi J Family Med Prim Care Case Report Amitraz is a worldwide available pesticide of formamidine chemical family, proven to have reversible toxic effects on both animals and humans. Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening. Because of lack of specific antidote patients are usually managed with supportive and symptomatic management. We describe a case of 36-year-old female patient who presented to us with alleged history of 120 ml amitraz ingestion. She was given early gastric lavage with activated charcoal at emergency along with supportive and symptomatic management. She developed mild CNS depression, bradycardia, miosis, and fluctuating blood pressure. She was managed in intensive care unit and was kept under close hemodynamic monitoring. Her clinical course during hospital stay was uneventful and was successfully discharged without any residual deficits. According to previously published data, this amount of amitraz intoxication could have caused more serious clinical manifestations. This disproportionately less severe clinical manifestation in our patient is attributed to early gastric lavage. Ominous of reducing amitraz-related health hazards lies in the hands of primary health care physicians and regulatory bodies of government. Wolters Kluwer - Medknow 2020-04-30 /pmc/articles/PMC7346969/ /pubmed/32670980 http://dx.doi.org/10.4103/jfmpc.jfmpc_1268_19 Text en Copyright: © 2020 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Madhuri, Pratti
Mukherjee, Anirudh
Manna, Sukdev
Dhar, Minakshi
Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_full Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_fullStr Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_full_unstemmed Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_short Amitraz poisoning: Early gastric lavage can prevent life-threatening complications
title_sort amitraz poisoning: early gastric lavage can prevent life-threatening complications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346969/
https://www.ncbi.nlm.nih.gov/pubmed/32670980
http://dx.doi.org/10.4103/jfmpc.jfmpc_1268_19
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