Cargando…

ERBB3-induced furin promotes the progression and metastasis of ovarian cancer via the IGF1R/STAT3 signaling axis

High-grade serous carcinoma, accounts for up to 70% of all ovarian cases. Furin, a proprotein convertase, is highly expressed in high-grade serous carcinoma of ovarian cancer patients, and its expression is even higher in tumor omentum than in normal omentum, the preferred site of ovarian cancer met...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Changliang, Gupta, Prachi, Parashar, Deepak, Nair, Gopakumar G, George, Jasmine, Geethadevi, Anjali, Wang, Wei, Tsaih, Shirng-Wern, Bradley, William, Ramchandran, Ramani, Rader, Janet S., Chaluvally-Raghavan, Pradeep, Pradeep, Sunila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346970/
https://www.ncbi.nlm.nih.gov/pubmed/32029900
http://dx.doi.org/10.1038/s41388-020-1194-7