MiR-1165-3p Suppresses Th2 Differentiation via Targeting IL-13 and PPM1A in a Mouse Model of Allergic Airway Inflammation

PURPOSE: CD4(+)T cells are essential in the pathogenesis of allergic asthma. We have previously demonstrated that microRNA-1165-3p (miR-1165-3p) was significantly reduced in T-helper type (Th) 2 cells and that miR-1165-3p was a surrogate marker for atopic asthma. Little is known about the mechanisms...

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Detalles Bibliográficos
Autores principales: Wang, Zhengxia, Ji, Ningfei, Chen, Zhongqi, Sun, Zhixiao, Wu, Chaojie, Yu, Wenqing, Hu, Fan, Huang, Mao, Zhang, Mingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346992/
https://www.ncbi.nlm.nih.gov/pubmed/32638565
http://dx.doi.org/10.4168/aair.2020.12.5.859

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