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In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection

Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory responses by stimulating pattern recognition recep...

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Detalles Bibliográficos
Autores principales: Miller, Amanda L., Pasternak, J. Alex, Medeiros, Nicole J., Nicastro, Lauren K., Tursi, Sarah A., Hansen, Elizabeth G., Krochak, Ryan, Sokaribo, Akosiererem S., MacKenzie, Keith D., Palmer, Melissa B., Herman, Dakoda J., Watson, Nikole L., Zhang, Yi, Wilson, Heather L., Wilson, R. Paul, White, Aaron P., Tükel, Çagla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347093/
https://www.ncbi.nlm.nih.gov/pubmed/32645118
http://dx.doi.org/10.1371/journal.ppat.1008591