Cargando…
In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica. Curli, an extracellular, bacterial amyloid with cross beta-sheet structure can trigger inflammatory responses by stimulating pattern recognition recep...
Autores principales: | Miller, Amanda L., Pasternak, J. Alex, Medeiros, Nicole J., Nicastro, Lauren K., Tursi, Sarah A., Hansen, Elizabeth G., Krochak, Ryan, Sokaribo, Akosiererem S., MacKenzie, Keith D., Palmer, Melissa B., Herman, Dakoda J., Watson, Nikole L., Zhang, Yi, Wilson, Heather L., Wilson, R. Paul, White, Aaron P., Tükel, Çagla |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347093/ https://www.ncbi.nlm.nih.gov/pubmed/32645118 http://dx.doi.org/10.1371/journal.ppat.1008591 |
Ejemplares similares
-
Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli
por: Tursi, Sarah A., et al.
Publicado: (2020) -
The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity
por: Biesecker, Steven G., et al.
Publicado: (2018) -
Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9
por: Tursi, Sarah A., et al.
Publicado: (2017) -
Nitrate Is an Environmental Cue in the Gut for Salmonella enterica Serovar Typhimurium Biofilm Dispersal through Curli Repression and Flagellum Activation via Cyclic-di-GMP Signaling
por: Miller, Amanda L., et al.
Publicado: (2022) -
Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice
por: Oppong, Gertrude O, et al.
Publicado: (2015)