Cargando…

Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics

INTRODUCTION: In 2012, the Centers for Disease Control and Prevention released updated guidelines recommending universal, one-time hepatitis C virus screening for all individuals born between 1945 and 1965. Prior to the implementation of these guidelines, testing rates were inappropriately low, but...

Descripción completa

Detalles Bibliográficos
Autores principales: Coppock, Dagan, Chou, Edgar, Gracely, Edward, Gross, Robert, Heun-Lee, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347094/
https://www.ncbi.nlm.nih.gov/pubmed/32645083
http://dx.doi.org/10.1371/journal.pone.0235778
_version_ 1783556525500923904
author Coppock, Dagan
Chou, Edgar
Gracely, Edward
Gross, Robert
Heun-Lee, Dong
author_facet Coppock, Dagan
Chou, Edgar
Gracely, Edward
Gross, Robert
Heun-Lee, Dong
author_sort Coppock, Dagan
collection PubMed
description INTRODUCTION: In 2012, the Centers for Disease Control and Prevention released updated guidelines recommending universal, one-time hepatitis C virus screening for all individuals born between 1945 and 1965. Prior to the implementation of these guidelines, testing rates were inappropriately low, but unnecessary duplicate antibody testing was also problematic. In the era of increased efforts to screen “baby boomers”, the prevalence and social determinants of initial and duplicate hepatitis C testing have not been well described. METHODS: A hepatitis C screening program was implemented at six urban primary care clinics affiliated with Drexel University College of Medicine. Data was collected regarding the screening patterns in these clinics. Annual screening rates for the program were assessed. Multivariate logistic regression analyses were used to examine the association of demographic variables and the outcomes of subjects having ever been tested and subjects having received duplicate testing. RESULTS: Following the implementation of the program, the screening rate increased from 16% in the first year of analysis to 82% in the final year of analysis. Of the 6,717 patients screened, 1,207 had duplicate testing, of which 14% had inappropriate duplicate antibody screening. African Americans and Asian patients had a higher odds of being screened. Patients with public insurance had a higher odds of duplicate screening. CONCLUSIONS: In the setting of an aggressive hepatitis C screening program, high testing rates may be attained in a target population. However, inappropriate duplicate antibody testing rates may be high, which may be a burden in resource-limited settings.
format Online
Article
Text
id pubmed-7347094
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-73470942020-07-17 Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics Coppock, Dagan Chou, Edgar Gracely, Edward Gross, Robert Heun-Lee, Dong PLoS One Research Article INTRODUCTION: In 2012, the Centers for Disease Control and Prevention released updated guidelines recommending universal, one-time hepatitis C virus screening for all individuals born between 1945 and 1965. Prior to the implementation of these guidelines, testing rates were inappropriately low, but unnecessary duplicate antibody testing was also problematic. In the era of increased efforts to screen “baby boomers”, the prevalence and social determinants of initial and duplicate hepatitis C testing have not been well described. METHODS: A hepatitis C screening program was implemented at six urban primary care clinics affiliated with Drexel University College of Medicine. Data was collected regarding the screening patterns in these clinics. Annual screening rates for the program were assessed. Multivariate logistic regression analyses were used to examine the association of demographic variables and the outcomes of subjects having ever been tested and subjects having received duplicate testing. RESULTS: Following the implementation of the program, the screening rate increased from 16% in the first year of analysis to 82% in the final year of analysis. Of the 6,717 patients screened, 1,207 had duplicate testing, of which 14% had inappropriate duplicate antibody screening. African Americans and Asian patients had a higher odds of being screened. Patients with public insurance had a higher odds of duplicate screening. CONCLUSIONS: In the setting of an aggressive hepatitis C screening program, high testing rates may be attained in a target population. However, inappropriate duplicate antibody testing rates may be high, which may be a burden in resource-limited settings. Public Library of Science 2020-07-09 /pmc/articles/PMC7347094/ /pubmed/32645083 http://dx.doi.org/10.1371/journal.pone.0235778 Text en © 2020 Coppock et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Coppock, Dagan
Chou, Edgar
Gracely, Edward
Gross, Robert
Heun-Lee, Dong
Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title_full Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title_fullStr Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title_full_unstemmed Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title_short Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
title_sort hepatitis c antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347094/
https://www.ncbi.nlm.nih.gov/pubmed/32645083
http://dx.doi.org/10.1371/journal.pone.0235778
work_keys_str_mv AT coppockdagan hepatitiscantibodyscreeninganddeterminantsofinitialandduplicatescreeninginthebabyboomerpatientsofsixurbanprimarycareclinics
AT chouedgar hepatitiscantibodyscreeninganddeterminantsofinitialandduplicatescreeninginthebabyboomerpatientsofsixurbanprimarycareclinics
AT gracelyedward hepatitiscantibodyscreeninganddeterminantsofinitialandduplicatescreeninginthebabyboomerpatientsofsixurbanprimarycareclinics
AT grossrobert hepatitiscantibodyscreeninganddeterminantsofinitialandduplicatescreeninginthebabyboomerpatientsofsixurbanprimarycareclinics
AT heunleedong hepatitiscantibodyscreeninganddeterminantsofinitialandduplicatescreeninginthebabyboomerpatientsofsixurbanprimarycareclinics