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Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period
Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint and is one of the most common orthopedic conditions in dogs. Due to the genetic contribution, most of the programs fighting against HD recommend selective breeding that excludes affected dogs. Using the best-scori...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347163/ https://www.ncbi.nlm.nih.gov/pubmed/32645070 http://dx.doi.org/10.1371/journal.pone.0235847 |
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author | Baldinger, Arnaud Genevois, Jean-Pierre Moissonnier, Pierre Barthélemy, Anthony Carozzo, Claude Viguier, Éric Cachon, Thibaut |
author_facet | Baldinger, Arnaud Genevois, Jean-Pierre Moissonnier, Pierre Barthélemy, Anthony Carozzo, Claude Viguier, Éric Cachon, Thibaut |
author_sort | Baldinger, Arnaud |
collection | PubMed |
description | Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint and is one of the most common orthopedic conditions in dogs. Due to the genetic contribution, most of the programs fighting against HD recommend selective breeding that excludes affected dogs. Using the best-scoring dogs for breeding may reduce the prevalence of HD. In France, the phenotypic screening of coxo-femoral joint conformation remains a strategy for breeders to establish selection decisions. The HD prevalence was evaluated in 10 breeds, based on the assessment of 27,710 dogs, during the 1997–2017 screening period, which was divided into 3 homogeneous cohorts for analysis. The global HD prevalence varied widely among breeds from 5% (Siberian Husky) to 51.9% (Cane Corso). It decreased over time in 6 breeds, among which 4 (Cane Corso, Gordon Setter, Rottweiler and White Swiss Shepherd) showed a significant decrease. A statistically significant increase in HD prevalence was noted for the Siberian Husky. Although the efficacy of phenotype-based breeding programs remains controversial, our results are in accordance with several recent studies showing that long-term selection policies are valuable, as they may help decreasing the HD prevalence in some breeds. The complementary use of more recent tools such as estimated breeding values and genomics would probably help breeders achieve more substantive results. |
format | Online Article Text |
id | pubmed-7347163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-73471632020-07-20 Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period Baldinger, Arnaud Genevois, Jean-Pierre Moissonnier, Pierre Barthélemy, Anthony Carozzo, Claude Viguier, Éric Cachon, Thibaut PLoS One Research Article Canine hip dysplasia (HD) is a complex developmental disease of the coxo-femoral joint and is one of the most common orthopedic conditions in dogs. Due to the genetic contribution, most of the programs fighting against HD recommend selective breeding that excludes affected dogs. Using the best-scoring dogs for breeding may reduce the prevalence of HD. In France, the phenotypic screening of coxo-femoral joint conformation remains a strategy for breeders to establish selection decisions. The HD prevalence was evaluated in 10 breeds, based on the assessment of 27,710 dogs, during the 1997–2017 screening period, which was divided into 3 homogeneous cohorts for analysis. The global HD prevalence varied widely among breeds from 5% (Siberian Husky) to 51.9% (Cane Corso). It decreased over time in 6 breeds, among which 4 (Cane Corso, Gordon Setter, Rottweiler and White Swiss Shepherd) showed a significant decrease. A statistically significant increase in HD prevalence was noted for the Siberian Husky. Although the efficacy of phenotype-based breeding programs remains controversial, our results are in accordance with several recent studies showing that long-term selection policies are valuable, as they may help decreasing the HD prevalence in some breeds. The complementary use of more recent tools such as estimated breeding values and genomics would probably help breeders achieve more substantive results. Public Library of Science 2020-07-09 /pmc/articles/PMC7347163/ /pubmed/32645070 http://dx.doi.org/10.1371/journal.pone.0235847 Text en © 2020 Baldinger et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Baldinger, Arnaud Genevois, Jean-Pierre Moissonnier, Pierre Barthélemy, Anthony Carozzo, Claude Viguier, Éric Cachon, Thibaut Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title | Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title_full | Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title_fullStr | Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title_full_unstemmed | Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title_short | Prevalence of canine hip dysplasia in 10 breeds in France, a retrospective study of the 1997-2017 radiographic screening period |
title_sort | prevalence of canine hip dysplasia in 10 breeds in france, a retrospective study of the 1997-2017 radiographic screening period |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347163/ https://www.ncbi.nlm.nih.gov/pubmed/32645070 http://dx.doi.org/10.1371/journal.pone.0235847 |
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