Characterization of a long-term mouse primary liver 3D tissue model recapitulating innate-immune responses and drug-induced liver toxicity

Three-dimensional liver in vitro systems have recently attracted a lot of attention in drug development. These systems help to gain unprecedented insights into drug-induced liver injury (DILI), as they more closely reproduce liver biology, and as drug effects can be studied in isolated and controlla...

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Detalles Bibliográficos
Autores principales: Nudischer, Ramona, Renggli, Kasper, Hierlemann, Andreas, Roth, Adrian B., Bertinetti-Lapatki, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347206/
https://www.ncbi.nlm.nih.gov/pubmed/32645073
http://dx.doi.org/10.1371/journal.pone.0235745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347206/
https://www.ncbi.nlm.nih.gov/pubmed/32645073
http://dx.doi.org/10.1371/journal.pone.0235745

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