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Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges

SARS-CoV-2 is a new member of coronaviruses that its sudden spreading put the health care system of most countries in a tremendous shock. For controlling of the new infection, COVID-19, many efforts have been done and are ongoing to defeat this virus in the combat field. In this review, we focused o...

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Autores principales: Hajivalili, Mahsa, Hosseini, Maryam, Haji-Fatahaliha, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347333/
https://www.ncbi.nlm.nih.gov/pubmed/32653518
http://dx.doi.org/10.1016/j.lfs.2020.118058
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author Hajivalili, Mahsa
Hosseini, Maryam
Haji-Fatahaliha, Mostafa
author_facet Hajivalili, Mahsa
Hosseini, Maryam
Haji-Fatahaliha, Mostafa
author_sort Hajivalili, Mahsa
collection PubMed
description SARS-CoV-2 is a new member of coronaviruses that its sudden spreading put the health care system of most countries in a tremendous shock. For controlling of the new infection, COVID-19, many efforts have been done and are ongoing to defeat this virus in the combat field. In this review, we focused on how the immune system behaves toward the virus and the relative possible consequences during their interactions. Then the therapeutic steps and potential vaccine candidates have been described in a hope to provide a better prospective of effective treatment and preventive strategies to the novel SARS-CoV in near future.
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spelling pubmed-73473332020-07-10 Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges Hajivalili, Mahsa Hosseini, Maryam Haji-Fatahaliha, Mostafa Life Sci Article SARS-CoV-2 is a new member of coronaviruses that its sudden spreading put the health care system of most countries in a tremendous shock. For controlling of the new infection, COVID-19, many efforts have been done and are ongoing to defeat this virus in the combat field. In this review, we focused on how the immune system behaves toward the virus and the relative possible consequences during their interactions. Then the therapeutic steps and potential vaccine candidates have been described in a hope to provide a better prospective of effective treatment and preventive strategies to the novel SARS-CoV in near future. Elsevier Inc. 2020-09-15 2020-07-09 /pmc/articles/PMC7347333/ /pubmed/32653518 http://dx.doi.org/10.1016/j.lfs.2020.118058 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Hajivalili, Mahsa
Hosseini, Maryam
Haji-Fatahaliha, Mostafa
Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title_full Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title_fullStr Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title_full_unstemmed Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title_short Gaining insights on immune responses to the novel coronavirus, COVID-19 and therapeutic challenges
title_sort gaining insights on immune responses to the novel coronavirus, covid-19 and therapeutic challenges
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347333/
https://www.ncbi.nlm.nih.gov/pubmed/32653518
http://dx.doi.org/10.1016/j.lfs.2020.118058
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