Does the hygiene hypothesis apply to COVID-19 susceptibility?

In this commentary we argue that the hygiene hypothesis may apply to COVID-19 susceptibility and also that residence in low hygienic conditions acts to train innate immune defenses to minimize the severity of infection. We advocate that approaches, which elevate innate immune functions, should be us...

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Detalles Bibliográficos
Autores principales: Sehrawat, Sharvan, Rouse, Barry T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Masson SAS on behalf of Institut Pasteur. 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347347/
https://www.ncbi.nlm.nih.gov/pubmed/32653475
http://dx.doi.org/10.1016/j.micinf.2020.07.002
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author Sehrawat, Sharvan
Rouse, Barry T.
author_facet Sehrawat, Sharvan
Rouse, Barry T.
author_sort Sehrawat, Sharvan
collection PubMed
description In this commentary we argue that the hygiene hypothesis may apply to COVID-19 susceptibility and also that residence in low hygienic conditions acts to train innate immune defenses to minimize the severity of infection. We advocate that approaches, which elevate innate immune functions, should be used to minimize the consequences of COVID-19 infection at least until effective vaccines and antiviral therapies are developed.
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spelling pubmed-73473472020-07-10 Does the hygiene hypothesis apply to COVID-19 susceptibility? Sehrawat, Sharvan Rouse, Barry T. Microbes Infect Commentary In this commentary we argue that the hygiene hypothesis may apply to COVID-19 susceptibility and also that residence in low hygienic conditions acts to train innate immune defenses to minimize the severity of infection. We advocate that approaches, which elevate innate immune functions, should be used to minimize the consequences of COVID-19 infection at least until effective vaccines and antiviral therapies are developed. Published by Elsevier Masson SAS on behalf of Institut Pasteur. 2020-10 2020-07-09 /pmc/articles/PMC7347347/ /pubmed/32653475 http://dx.doi.org/10.1016/j.micinf.2020.07.002 Text en © 2020 Published by Elsevier Masson SAS on behalf of Institut Pasteur. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Commentary
Sehrawat, Sharvan
Rouse, Barry T.
Does the hygiene hypothesis apply to COVID-19 susceptibility?
title Does the hygiene hypothesis apply to COVID-19 susceptibility?
title_full Does the hygiene hypothesis apply to COVID-19 susceptibility?
title_fullStr Does the hygiene hypothesis apply to COVID-19 susceptibility?
title_full_unstemmed Does the hygiene hypothesis apply to COVID-19 susceptibility?
title_short Does the hygiene hypothesis apply to COVID-19 susceptibility?
title_sort does the hygiene hypothesis apply to covid-19 susceptibility?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347347/
https://www.ncbi.nlm.nih.gov/pubmed/32653475
http://dx.doi.org/10.1016/j.micinf.2020.07.002
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