Cargando…

Update on DNA-Double Strand Break Repair Defects in Combined Primary Immunodeficiency

PURPOSE OF REVIEW: The most serious DNA damage, DNA double strand breaks (DNA-dsb), leads to mutagenesis, carcinogenesis or apoptosis if left unrepaired. Non-homologous end joining (NHEJ) is the principle repair pathway employed by mammalian cells to repair DNA-dsb. Several proteins are involved in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Slatter, Mary A., Gennery, Andrew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Immune Deficiency and Dysregulation (C Kuo, Section Editor)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347510/ https://www.ncbi.nlm.nih.gov/pubmed/32648006 http://dx.doi.org/10.1007/s11882-020-00955-z

Ejemplares similares

Conditioning Regimens for Hematopoietic Cell Transplantation in Primary Immunodeficiency
por: Lum, S. H., et al.
Publicado: (2019)

Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions
por: James, Louisa K., et al.
Publicado: (2016)

IgG4 Characteristics and Functions in Cancer Immunity
por: Crescioli, Silvia, et al.
Publicado: (2016)

Dysregulation of Group 3 Innate Lymphoid Cells in the Pathogenesis of Inflammatory Bowel Disease
por: Forkel, Marianne, et al.
Publicado: (2016)

Mechanisms of Respiratory Syncytial Virus Modulation of Airway Immune Responses
por: Lotz, Matthew T., et al.
Publicado: (2012)

Splice-Correction Strategies for Treatment of X-Linked Agammaglobulinemia
por: Bestas, Burcu, et al.
Publicado: (2015)

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency()
por: Hassan, Amel, et al.
Publicado: (2014)

An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex
por: Kracker, Sven, et al.
Publicado: (2015)

Pathological mutations in PNKP trigger defects in DNA single-strand break repair but not DNA double-strand break repair
por: Kalasova, Ilona, et al.
Publicado: (2020)

Repair of DNA Double-Strand Breaks in Heterochromatin
por: Watts, Felicity Z.
Publicado: (2016)

Lymphocyte subsets in healthy Malawians: Implications for immunologic assessment of HIV infection in Africa
por: Mandala, Wilson L., et al.
Publicado: (2010)

Pattern recognition receptor-mediated cytokine response in infants across 4 continents(⋆)()
por: Smolen, Kinga K., et al.
Publicado: (2014)

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency
por: Lang, Philipp A., et al.
Publicado: (2013)

B-cell reconstitution after lentiviral vector–mediated gene therapy in patients with Wiskott-Aldrich syndrome
por: Castiello, Maria Carmina, et al.
Publicado: (2015)

Effects of maternal geohelminth infections on allergy in early childhood
por: Cooper, Philip J., et al.
Publicado: (2016)

Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding
por: Cetica, Valentina, et al.
Publicado: (2015)

Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry
por: Cetica, Valentina, et al.
Publicado: (2016)

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
por: Coulter, Tanya I., et al.
Publicado: (2017)

Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells
por: Chen, Hannah H., et al.
Publicado: (2017)

Respiratory syncytial virus infection activates IL-13–producing group 2 innate lymphoid cells through thymic stromal lymphopoietin
por: Stier, Matthew T., et al.
Publicado: (2016)

DNA double-strand break repair in Caenorhabditis elegans
por: Lemmens, Bennie B. L. G., et al.
Publicado: (2010)

Nampt is involved in DNA double-strand break repair
por: Zhu, Bingtao, et al.
Publicado: (2012)

The Chromatin Response to Double-Strand DNA Breaks and Their Repair
por: Aleksandrov, Radoslav, et al.
Publicado: (2020)

The roles of RNA in DNA double-strand break repair
por: Bader, Aldo S., et al.
Publicado: (2020)

ATM’s Role in the Repair of DNA Double-Strand Breaks
por: Shibata, Atsushi, et al.
Publicado: (2021)

Excess Single-Stranded DNA Inhibits Meiotic Double-Strand Break Repair
por: Johnson, Rebecca, et al.
Publicado: (2007)

A New Light on Vitamines
Publicado: (1921)

Responder analysis for improvement in 6‐min walk test with ferric carboxymaltose in patients with heart failure with reduced ejection fraction and iron deficiency
por: Anker, Stefan D., et al.
Publicado: (2022)

Health status improvement with ferric carboxymaltose in heart failure with reduced ejection fraction and iron deficiency
por: Butler, Javed, et al.
Publicado: (2022)

DNA Double-Strand Break Repairs and Their Application in Plant DNA Integration
por: Shen, Hexi, et al.
Publicado: (2022)

DNA double-strand break repair and the evolution of intron density
por: Farlow, Ashley, et al.
Publicado: (2011)

Erratum to: DNA double-strand break repair in Caenorhabditis elegans
por: Lemmens, Bennie B. L. G., et al.
Publicado: (2011)

Chromatin modifications and DNA repair: beyond double-strand breaks
por: House, Nealia C. M., et al.
Publicado: (2014)

FKBP25 participates in DNA double-strand break repair()
por: Dilworth, David, et al.
Publicado: (2019)

Harnessing DNA Double-Strand Break Repair for Cancer Treatment
por: Trenner, Anika, et al.
Publicado: (2019)

The formation and repair of DNA double-strand breaks in mammalian meiosis
por: Qu, Wei, et al.
Publicado: (2021)

Meiotic Genes and DNA Double Strand Break Repair in Cancer
por: Lingg, Lea, et al.
Publicado: (2022)

Histone acetylation dynamics in repair of DNA double-strand breaks
por: Aricthota, Shalini, et al.
Publicado: (2022)

Hematopoietic Stem Cell Transplantation for DNA Double Strand Breakage Repair Disorders
por: Wolska-Kuśnierz, Beata, et al.
Publicado: (2020)

Pathologic Replication-Independent Endogenous DNA Double-Strand Breaks Repair Defect in Chronological Aging Yeast
por: Pongpanich, Monnat, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_t72fmki52ilukpcn493ea3rp29