Cargando…

Aging increases the systemic molecular degree of inflammatory perturbation in patients with tuberculosis

Tuberculosis (TB) is a chronic infection that can affect individuals of all ages. The description of determinants of immunopathogenesis in TB is of tremendous interest due to the perspective of finding a reliable host-directed therapy to reduce disease burden. The association between specific biomar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oliveira-de-Souza, Deivide, Vinhaes, Caian L., Arriaga, María B., Kumar, Nathella Pavan, Queiroz, Artur T. L., Fukutani, Kiyoshi F., Babu, Subash, Andrade, Bruno B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347549/ https://www.ncbi.nlm.nih.gov/pubmed/32647178 http://dx.doi.org/10.1038/s41598-020-68255-0

Ejemplares similares

Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations
por: Oliveira-de-Souza, Deivide, et al.
Publicado: (2019)

Dissecting disease tolerance in Plasmodium vivax malaria using the systemic degree of inflammatory perturbation
por: Vinhaes, Caian L., et al.
Publicado: (2021)

A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
por: Queiroz, Artur T. L., et al.
Publicado: (2023)

Chronic Hepatitis B Infection Is Associated with Increased Molecular Degree of Inflammatory Perturbation in Peripheral Blood
por: Vinhaes, Caian L., et al.
Publicado: (2020)

Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome – a case report of a complicated scenario
por: Narendran, Gopalan, et al.
Publicado: (2019)

In silico transcriptional analysis of mRNA and miRNA reveals unique biosignatures that characterizes different types of diabetes
por: Cubillos-Angulo, Juan M., et al.
Publicado: (2020)

Hydroxyurea treatment is associated with reduced degree of oxidative perturbation in children and adolescents with sickle cell anemia
por: Vinhaes, Caian L., et al.
Publicado: (2020)

Differential expression of CXCR3 and CCR6 on CD4(+) T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome
por: Silveira-Mattos, Paulo S., et al.
Publicado: (2019)

Author Correction: Differential expression of CXCR3 and CCR6 on CD4(+) T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome
por: Silveira-Mattos, Paulo S., et al.
Publicado: (2019)

Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity
por: Kumar, Nathella Pavan, et al.
Publicado: (2019)

Host Inflammatory Biomarkers of Disease Severity in Pediatric Community-Acquired Pneumonia: A Systematic Review and Meta-analysis
por: Fernandes, Catarina D, et al.
Publicado: (2019)

Impact of diabetes mellitus on immunity to latent tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2023)

Zika-exposed microcephalic neonates exhibit higher degree of inflammatory imbalance in cerebrospinal fluid
por: Nascimento-Carvalho, Gustavo C., et al.
Publicado: (2021)

Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications
por: Prada-Medina, Cesar A., et al.
Publicado: (2017)

Heightened Plasma Levels of Transforming Growth Factor Beta (TGF-β) and Increased Degree of Systemic Biochemical Perturbation Characterizes Hepatic Steatosis in Overweight Pediatric Patients: A Cross-Sectional Study
por: Barretto, Junaura R., et al.
Publicado: (2020)

Evidence of Microbial Translocation Associated with Perturbations in T Cell and Antigen-Presenting Cell Homeostasis in Hookworm Infections
por: George, Palakkal Jovvian, et al.
Publicado: (2012)

Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2016)

Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Systems biology analysis of publicly available transcriptomic data reveals a critical link between AKR1B10 gene expression, smoking and occurrence of lung cancer
por: Cubillos-Angulo, Juan M., et al.
Publicado: (2020)

Correlation Between SARS-Cov-2 Vaccination, COVID-19 Incidence and Mortality: Tracking the Effect of Vaccination on Population Protection in Real Time
por: Fukutani, Kiyoshi F., et al.
Publicado: (2021)

Role of myeloid derived suppressor cells in tuberculosis infection and disease
por: Kumar, Nathella Pavan, et al.
Publicado: (2014)

Host-directed therapies in pulmonary tuberculosis: Updates on anti-inflammatory drugs
por: Cubillos-Angulo, Juan M., et al.
Publicado: (2022)

Effect of anti-tuberculosis treatment on the systemic levels of tissue inhibitors of metalloproteinases in tuberculosis – Diabetes co-morbidity
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Prediabetes is associated with the modulation of antigen-specific Th1/Tc1 and Th17/Tc17 responses in latent Mycobacterium tuberculosis infection
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Coincident Pre-Diabetes Is Associated with Dysregulated Cytokine Responses in Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2014)

High Dimensionality Reduction and Immune Phenotyping of Natural Killer and Invariant Natural Killer Cells in Latent Tuberculosis-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

Plasma Heme Oxygenase-1 Levels Distinguish Latent or Successfully Treated Human Tuberculosis from Active Disease
por: Andrade, Bruno B., et al.
Publicado: (2013)

Decreased Frequencies of Circulating CD4(+) T Follicular Helper Cells Associated with Diminished Plasma IL-21 in Active Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2014)

Relationship Between Anemia and Systemic Inflammation in People Living With HIV and Tuberculosis: A Sub-Analysis of the CADIRIS Clinical Trial
por: Araújo-Pereira, Mariana, et al.
Publicado: (2022)

Decreased Frequencies of Gamma/Delta T Cells Expressing Th1/Th17 Cytokine, Cytotoxic, and Immune Markers in Latent Tuberculosis-Diabetes/Pre-Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2021)

Multi-Dimensionality Immunophenotyping Analyses of MAIT Cells Expressing Th1/Th17 Cytokines and Cytotoxic Markers in Latent Tuberculosis Diabetes Comorbidity
por: Kathamuthu, Gokul Raj, et al.
Publicado: (2022)

Plasma Eicosanoid Levels in Tuberculosis and Tuberculosis-Diabetes Co-morbidity Are Associated With Lung Pathology and Bacterial Burden
por: Pavan Kumar, Nathella, et al.
Publicado: (2019)

Heightened circulating levels of antimicrobial peptides in tuberculosis—Diabetes co-morbidity and reversal upon treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy
por: Kumar, Nathella Pavan, et al.
Publicado: (2019)

Systemic Inflammation Associated with Immune Reconstitution Inflammatory Syndrome in Persons Living with HIV
por: Vinhaes, Caian L., et al.
Publicado: (2021)

Helminth Infections Coincident with Active Pulmonary Tuberculosis Inhibit Mono- and Multifunctional CD4(+) and CD8(+) T Cell Responses in a Process Dependent on IL-10
por: George, Parakkal Jovvian, et al.
Publicado: (2014)

Acute Phase Proteins Are Baseline Predictors of Tuberculosis Treatment Failure
por: Kumar, Nathella Pavan, et al.
Publicado: (2021)

Coincident Helminth Infection Modulates Systemic Inflammation and Immune Activation in Active Pulmonary Tuberculosis
por: George, Parakkal Jovvian, et al.
Publicado: (2014)

IL-10 Dependent Suppression of Type 1, Type 2 and Type 17 Cytokines in Active Pulmonary Tuberculosis
por: Kumar, Nathella Pavan, et al.
Publicado: (2013)

Multidimensional Analysis of Food Consumption Reveals a Unique Dietary Profile Associated with Overweight and Obesity in Adolescents
por: Andrade, Vanessa M.B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_imgo4bcknro33g0k8bhfrfkml1