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TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells

The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplastic mammary epithelial and cancer stem cells to reve...

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Detalles Bibliográficos
Autores principales: Remšík, Ján, Pícková, Markéta, Vacek, Ondřej, Fedr, Radek, Binó, Lucia, Hampl, Aleš, Souček, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347574/
https://www.ncbi.nlm.nih.gov/pubmed/32647280
http://dx.doi.org/10.1038/s41598-020-67827-4