EEF1A1 deacetylation enables transcriptional activation of remyelination

Remyelination of the peripheral and central nervous systems (PNS and CNS, respectively) is a prerequisite for functional recovery after lesion. However, this process is not always optimal and becomes inefficient in the course of multiple sclerosis. Here we show that, when acetylated, eukaryotic elon...

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Detalles Bibliográficos
Autores principales: Duman, Mert, Vaquié, Adrien, Nocera, Gianluigi, Heller, Manfred, Stumpe, Michael, Siva Sankar, Devanarayanan, Dengjel, Jörn, Meijer, Dies, Yamaguchi, Teppei, Matthias, Patrick, Zeis, Thomas, Schaeren-Wiemers, Nicole, Hayoz, Antoinette, Ruff, Sophie, Jacob, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347577/
https://www.ncbi.nlm.nih.gov/pubmed/32647127
http://dx.doi.org/10.1038/s41467-020-17243-z

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