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Celastrol inhibits ezrin-mediated migration of hepatocellular carcinoma cells

Progression of hepatocellular carcinoma involves multiple genetic and epigenetic alterations that promote cancer invasion and metastasis. Our recent study revealed that hyperphosphorylation of ezrin promotes intrahepatic metastasis in vivo and cell migration in vitro. Celastrol is a natural product...

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Detalles Bibliográficos
Autores principales:	Du, Shihao, Song, Xiaoyu, Li, Yuan, Cao, Yalei, Chu, Fuhao, Durojaye, Olanrewaju Ayodeji, Su, Zeqi, Shi, Xiaoguang, Wang, Jing, Cheng, Juan, Wang, Tangshun, Gao, Xiang, Chen, Yan, Zeng, Wuzhekai, Wang, Fengsong, Wang, DongMei, Liu, Xing, Ding, Xia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347585/ https://www.ncbi.nlm.nih.gov/pubmed/32647287 http://dx.doi.org/10.1038/s41598-020-68238-1

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