Cargando…
Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses
AhR is a ligand-activated transcription factor that plays an important role in the innate and adaptive immune responses. In infection models, it has been associated with host responses that promote or inhibit disease progression. In pulmonary paracoccidioidomycosis, a primary fungal infection endemi...
Autores principales: | de Araújo, Eliseu Frank, Preite, Nycolas Willian, Veldhoen, Marc, Loures, Flávio Vieira, Calich, Vera Lúcia Garcia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347857/ https://www.ncbi.nlm.nih.gov/pubmed/32647342 http://dx.doi.org/10.1038/s41598-020-68322-6 |
Ejemplares similares
-
The IDO–AhR Axis Controls Th17/Treg Immunity in a Pulmonary Model of Fungal Infection
por: de Araújo, Eliseu Frank, et al.
Publicado: (2017) -
Myeloid-derived suppressor cells are associated with impaired Th1 and Th17 responses and severe pulmonary paracoccidioidomycosis which is reversed by anti-Gr1 therapy
por: Preite, Nycolas Willian, et al.
Publicado: (2023) -
AhR Ligands Modulate the Differentiation of Innate Lymphoid Cells and T Helper Cell Subsets That Control the Severity of a Pulmonary Fungal Infection
por: de Araújo, Eliseu F., et al.
Publicado: (2021) -
Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome
por: Galdino, Nayane A. L., et al.
Publicado: (2018) -
The immunosuppressive activity of myeloid-derived suppressor cells in murine Paracoccidioidomycosis relies on Indoleamine 2,3-dioxygenase activity and Dectin-1 and TLRs signaling
por: Kaminski, Valéria de Lima, et al.
Publicado: (2023)