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Regional transcriptome analysis of AMPA and GABA(A) receptor subunit expression generates E/I signatures of the human brain

Theoretical and experimental work has demonstrated that excitatory (E) and inhibitory (I) currents within cortical circuits stabilize to a balanced state. This E/I balance, observed from single neuron to network levels, has a fundamental role in proper brain function and its impairment has been link...

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Detalles Bibliográficos
Autores principales: Shen, Kevin, Zeppillo, Tommaso, Limon, Agenor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347860/
https://www.ncbi.nlm.nih.gov/pubmed/32647210
http://dx.doi.org/10.1038/s41598-020-68165-1