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Doxorubicin-loaded iron oxide nanoparticles for glioblastoma therapy: a combinational approach for enhanced delivery of nanoparticles

Although doxorubicin (DOX) is an effective anti-cancer drug with cytotoxicity in a variety of different tumors, its effectiveness in treating glioblastoma multiforme (GBM) is constrained by insufficient penetration across the blood–brain barrier (BBB). In this study, biocompatible magnetic iron oxid...

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Detalles Bibliográficos
Autores principales: Norouzi, Mohammad, Yathindranath, Vinith, Thliveris, James A., Kopec, Brian M., Siahaan, Teruna J., Miller, Donald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347880/
https://www.ncbi.nlm.nih.gov/pubmed/32647151
http://dx.doi.org/10.1038/s41598-020-68017-y