Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38(MAPK)-MK2 axis and affects NF-κB-mediated transcription

Steroid receptor coactivator-3 (SRC-3) regulates the activity of both nuclear hormone receptors and a number of key transcription factors. It is implicated in the regulation of cell proliferation, inflammation and in the progression of several common cancers including breast, colorectal and lung tum...

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Detalles Bibliográficos
Autores principales: Shrestha, Anup, Bruckmueller, Henrike, Kildalsen, Hanne, Kaur, Gurjit, Gaestel, Matthias, Wetting, Hilde Ljones, Mikkola, Ingvild, Seternes, Ole-Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347898/
https://www.ncbi.nlm.nih.gov/pubmed/32647362
http://dx.doi.org/10.1038/s41598-020-68219-4

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