Cargando…
Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex
Metacognitive awareness—the ability to know that one is having a particular experience—is thought to guide optimal behavior, but its neural bases continue to be the subject of vigorous debate. Prior work has identified correlations between perceptual metacognitive ability and the structure and funct...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347936/ https://www.ncbi.nlm.nih.gov/pubmed/32647260 http://dx.doi.org/10.1038/s42003-020-1049-3 |
_version_ | 1783556689951195136 |
---|---|
author | Lapate, Regina C. Samaha, Jason Rokers, Bas Postle, Bradley R. Davidson, Richard J. |
author_facet | Lapate, Regina C. Samaha, Jason Rokers, Bas Postle, Bradley R. Davidson, Richard J. |
author_sort | Lapate, Regina C. |
collection | PubMed |
description | Metacognitive awareness—the ability to know that one is having a particular experience—is thought to guide optimal behavior, but its neural bases continue to be the subject of vigorous debate. Prior work has identified correlations between perceptual metacognitive ability and the structure and function of lateral prefrontal cortex (LPFC); however, evidence for a causal role of this region in promoting metacognition is controversial. Moreover, whether LPFC function promotes metacognitive awareness of perceptual and emotional features of complex, yet ubiquitous face stimuli is unknown. Here, using model-based analyses following a causal intervention to LPFC in humans, we demonstrate that LPFC function promotes metacognitive awareness of the orientation of faces—although not of their emotional expressions. Collectively, these data support the causal involvement of the prefrontal cortex in metacognitive awareness, and indicate that the role of LPFC in metacognition encompasses perceptual experiences of naturalistic social stimuli. |
format | Online Article Text |
id | pubmed-7347936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-73479362020-07-13 Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex Lapate, Regina C. Samaha, Jason Rokers, Bas Postle, Bradley R. Davidson, Richard J. Commun Biol Article Metacognitive awareness—the ability to know that one is having a particular experience—is thought to guide optimal behavior, but its neural bases continue to be the subject of vigorous debate. Prior work has identified correlations between perceptual metacognitive ability and the structure and function of lateral prefrontal cortex (LPFC); however, evidence for a causal role of this region in promoting metacognition is controversial. Moreover, whether LPFC function promotes metacognitive awareness of perceptual and emotional features of complex, yet ubiquitous face stimuli is unknown. Here, using model-based analyses following a causal intervention to LPFC in humans, we demonstrate that LPFC function promotes metacognitive awareness of the orientation of faces—although not of their emotional expressions. Collectively, these data support the causal involvement of the prefrontal cortex in metacognitive awareness, and indicate that the role of LPFC in metacognition encompasses perceptual experiences of naturalistic social stimuli. Nature Publishing Group UK 2020-07-09 /pmc/articles/PMC7347936/ /pubmed/32647260 http://dx.doi.org/10.1038/s42003-020-1049-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Lapate, Regina C. Samaha, Jason Rokers, Bas Postle, Bradley R. Davidson, Richard J. Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title | Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title_full | Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title_fullStr | Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title_full_unstemmed | Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title_short | Perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
title_sort | perceptual metacognition of human faces is causally supported by function of the lateral prefrontal cortex |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347936/ https://www.ncbi.nlm.nih.gov/pubmed/32647260 http://dx.doi.org/10.1038/s42003-020-1049-3 |
work_keys_str_mv | AT lapatereginac perceptualmetacognitionofhumanfacesiscausallysupportedbyfunctionofthelateralprefrontalcortex AT samahajason perceptualmetacognitionofhumanfacesiscausallysupportedbyfunctionofthelateralprefrontalcortex AT rokersbas perceptualmetacognitionofhumanfacesiscausallysupportedbyfunctionofthelateralprefrontalcortex AT postlebradleyr perceptualmetacognitionofhumanfacesiscausallysupportedbyfunctionofthelateralprefrontalcortex AT davidsonrichardj perceptualmetacognitionofhumanfacesiscausallysupportedbyfunctionofthelateralprefrontalcortex |