Tumour budding, poorly differentiated clusters, and T-cell response in colorectal cancer

BACKGROUND: Tumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and PDC in colorectal carcinoma. METHODS: Utilising 915 colon and...

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Detalles Bibliográficos
Autores principales: Fujiyoshi, Kenji, Väyrynen, Juha P., Borowsky, Jennifer, Papke, David J., Arima, Kota, Haruki, Koichiro, Kishikawa, Junko, Akimoto, Naohiko, Ugai, Tomotaka, Lau, Mai Chan, Gu, Simeng, Shi, Shanshan, Zhao, Melissa, Da Silva, Annacarolina Fabiana Lucia, Twombly, Tyler S., Nan, Hongmei, Meyerhardt, Jeffrey A., Song, Mingyang, Zhang, Xuehong, Wu, Kana, Chan, Andrew T., Fuchs, Charles S., Lennerz, Jochen K., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347996/
https://www.ncbi.nlm.nih.gov/pubmed/32652320
http://dx.doi.org/10.1016/j.ebiom.2020.102860

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