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OSBPL2 Is Required for the Binding of COPB1 to ATGL and the Regulation of Lipid Droplet Lipolysis
The accumulation of giant lipid droplets (LDs) increases the risk of metabolic disorders including obesity and insulin resistance. The lipolysis process involves the activation and transfer of lipase, but the molecular mechanism is not completely understood. The translocation of ATGL, a critical lip...
Autores principales: | Wang, Tianming, Wei, Qinjun, Liang, Lihong, Tang, Xujun, Yao, Jun, Lu, Yajie, Qu, Yuan, Chen, Zhibin, Xing, Guangqian, Cao, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348002/ https://www.ncbi.nlm.nih.gov/pubmed/32650117 http://dx.doi.org/10.1016/j.isci.2020.101252 |
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