Cargando…

Exendin‐4, a GLP‐1 receptor agonist regulates retinal capillary tone and restores microvascular patency after ischaemia–reperfusion injury

BACKGROUND AND PURPOSE: The aim of this study is to investigate the vasorelaxant effect of exendin‐4, a GLP‐1 receptor agonist on retinal capillaries under normal and ischaemia–reperfusion (I/R) conditions. EXPERIMENTAL APPROACH: Capillary diameters in the whole‐mounted retina were directly observed...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhai, Ruyi, Xu, Huan, Hu, Fangyuan, Wu, Jihong, Kong, Xiangmei, Sun, Xinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348095/
https://www.ncbi.nlm.nih.gov/pubmed/32232832
http://dx.doi.org/10.1111/bph.15059