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Lestaurtinib potentiates TRAIL‐induced apoptosis in glioma via CHOP‐dependent DR5 induction

Lestaurtinib, also called CEP‐701, is an inhibitor of tyrosine kinase, causes haematological remission in patients with AML possessing FLT3‐ITD (FLT3 gene) internal tandem duplication and strongly inhibits tyrosine kinase FLT3. Treatment with lestaurtinib modulates various signalling pathways and le...

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Detalles Bibliográficos
Autores principales:	Cao, Yingxiao, Kong, Shiqi, Xin, Yuling, Meng, Yan, Shang, Shuling, Qi, Yanhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348155/ https://www.ncbi.nlm.nih.gov/pubmed/32441887 http://dx.doi.org/10.1111/jcmm.15415

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