Asiaticoside might attenuate bleomycin‐induced pulmonary fibrosis by activating cAMP and Rap1 signalling pathway assisted by A2AR

Asiaticoside (AS) has been reported to have protective effect on pulmonary fibrosis (PF). In this study, we aimed to explore the potential mechanism of the therapeutic role of AS and its relationship with A2AR in PF. Adenosine 2A receptor gene knockout (A2AR(−/−)) mice and wild‐type (WT) mice were u...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Zhang, Ting, Zhu, Chengwei, Sun, Junwei, Zhu, Wenjing, Ai, Wenxiu, Huang, Xiaoying, Wang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348182/
https://www.ncbi.nlm.nih.gov/pubmed/32548952
http://dx.doi.org/10.1111/jcmm.15505

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