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CXCR4/STAT3在骨髓基质细胞介导的急性髓系白血病耐药中的作用研究

OBJECTIVE: To explore the role of CXCR4/STAT3 in mesenchymal stromal cell (MSC)-mediated drug resistance of AML cells. METHODS: AML cell lines U937 and KG1a and primary AML cells were co-cultured with MSC from bone marrow of healthy donors. The AML cell lines cultured alone were used as control. Apo...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348206/
https://www.ncbi.nlm.nih.gov/pubmed/27014981
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2016.02.007