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热休克蛋白90抑制剂17-AAG对HUT-102细胞株JAK3/STAT5信号通路的影响

OBJECTIVE: To analyze whether heat-shock protein 90 (HSP90) be involved in a permanently abnormal activated JAK/STAT signaling in ATL cells in vitro. METHODS: The effect of 17-AAG on proliferation of ATL cell lines HUT-102 was assessed using CCK8 at different time points. Cell apoptosis was measured...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348253/
https://www.ncbi.nlm.nih.gov/pubmed/28954352
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2017.08.012