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Passive immunization

Immediate protection of an animal can be achieved by passive immunization—the administration of preformed antibodies to a susceptible animal. These antibodies have historically been produced in hyperimmunized horses. The most widely employed are antitoxins directed against clostridia, such as tetanu...

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Detalles Bibliográficos
Autor principal: Tizard, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348624/
http://dx.doi.org/10.1016/B978-0-323-68299-2.00021-6
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author Tizard, Ian R.
author_facet Tizard, Ian R.
author_sort Tizard, Ian R.
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description Immediate protection of an animal can be achieved by passive immunization—the administration of preformed antibodies to a susceptible animal. These antibodies have historically been produced in hyperimmunized horses. The most widely employed are antitoxins directed against clostridia, such as tetanus or botulism, and snake venoms. Polyclonal antibodies are also administered to neonatal animals to protect against infections such as Rhodococcus equi in foals. Monoclonal antibodies are more specific reagents that are currently being used for the treatment of atopic dermatitis, certain cancers, and selected infectious diseases. Intravenous immunoglobulins are being used to treat autoimmune diseases.
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spelling pubmed-73486242020-07-10 Passive immunization Tizard, Ian R. Vaccines for Veterinarians Article Immediate protection of an animal can be achieved by passive immunization—the administration of preformed antibodies to a susceptible animal. These antibodies have historically been produced in hyperimmunized horses. The most widely employed are antitoxins directed against clostridia, such as tetanus or botulism, and snake venoms. Polyclonal antibodies are also administered to neonatal animals to protect against infections such as Rhodococcus equi in foals. Monoclonal antibodies are more specific reagents that are currently being used for the treatment of atopic dermatitis, certain cancers, and selected infectious diseases. Intravenous immunoglobulins are being used to treat autoimmune diseases. 2021 2020-07-10 /pmc/articles/PMC7348624/ http://dx.doi.org/10.1016/B978-0-323-68299-2.00021-6 Text en Copyright © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Tizard, Ian R.
Passive immunization
title Passive immunization
title_full Passive immunization
title_fullStr Passive immunization
title_full_unstemmed Passive immunization
title_short Passive immunization
title_sort passive immunization
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348624/
http://dx.doi.org/10.1016/B978-0-323-68299-2.00021-6
work_keys_str_mv AT tizardianr passiveimmunization