Cargando…

Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease

Parkinson’s disease (PD) is the second most frequent neurodegenerative disease of people who are beyond 50 years of age. People with PD (PwP) suffer from a large variety of motor and non-motor symptoms resulting in reduced health-related quality of life (HR-QoL). In the last two decades, alexithymia...

Descripción completa

Detalles Bibliográficos
Autores principales: Klietz, Martin, Schnur, Theresa, Drexel, Simon C., Lange, Florian, Paracka, Lejla, Huber, Meret K., Dressler, Dirk, Höglinger, Günter U., Wegner, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348697/
https://www.ncbi.nlm.nih.gov/pubmed/32599704
http://dx.doi.org/10.3390/brainsci10060401
_version_ 1783556885873426432
author Klietz, Martin
Schnur, Theresa
Drexel, Simon C.
Lange, Florian
Paracka, Lejla
Huber, Meret K.
Dressler, Dirk
Höglinger, Günter U.
Wegner, Florian
author_facet Klietz, Martin
Schnur, Theresa
Drexel, Simon C.
Lange, Florian
Paracka, Lejla
Huber, Meret K.
Dressler, Dirk
Höglinger, Günter U.
Wegner, Florian
author_sort Klietz, Martin
collection PubMed
description Parkinson’s disease (PD) is the second most frequent neurodegenerative disease of people who are beyond 50 years of age. People with PD (PwP) suffer from a large variety of motor and non-motor symptoms resulting in reduced health-related quality of life (HR-QoL). In the last two decades, alexithymia was identified as an additional non-motor symptom in PD. Alexithymia is defined as a cognitive affective disturbance resulting in difficulty to identify and distinguish feelings from bodily sensations of emotional arousal. In PD, the frequency of patients suffering of alexithymia is increased compared to healthy controls. The aim of the present study was to determine the relationship of alexithymia to HR-QoL of the PwP and caregiver burden of the corresponding caregiver. This cross-sectional questionnaire-based study used disease specific questionnaires for HR-QoL and caregiver burden. In total 119 PwP and their corresponding caregivers were included in the study. HR-QoL of the PwP correlated significantly with alexithymia (p < 0.001), especially the sub-components “identifying feelings” (p < 0.001) and “difficulties describing feelings” (p = 0.001). Caregiver burden also correlated significantly with PwP alexithymia (p < 0.001). However, caregiver burden was associated with sub-components “identifying feelings” (p < 0.008) and “external oriented thinking” (p < 0.004). These data support the importance of alexithymia as a non-motor symptom in PD.
format Online
Article
Text
id pubmed-7348697
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-73486972020-07-20 Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease Klietz, Martin Schnur, Theresa Drexel, Simon C. Lange, Florian Paracka, Lejla Huber, Meret K. Dressler, Dirk Höglinger, Günter U. Wegner, Florian Brain Sci Article Parkinson’s disease (PD) is the second most frequent neurodegenerative disease of people who are beyond 50 years of age. People with PD (PwP) suffer from a large variety of motor and non-motor symptoms resulting in reduced health-related quality of life (HR-QoL). In the last two decades, alexithymia was identified as an additional non-motor symptom in PD. Alexithymia is defined as a cognitive affective disturbance resulting in difficulty to identify and distinguish feelings from bodily sensations of emotional arousal. In PD, the frequency of patients suffering of alexithymia is increased compared to healthy controls. The aim of the present study was to determine the relationship of alexithymia to HR-QoL of the PwP and caregiver burden of the corresponding caregiver. This cross-sectional questionnaire-based study used disease specific questionnaires for HR-QoL and caregiver burden. In total 119 PwP and their corresponding caregivers were included in the study. HR-QoL of the PwP correlated significantly with alexithymia (p < 0.001), especially the sub-components “identifying feelings” (p < 0.001) and “difficulties describing feelings” (p = 0.001). Caregiver burden also correlated significantly with PwP alexithymia (p < 0.001). However, caregiver burden was associated with sub-components “identifying feelings” (p < 0.008) and “external oriented thinking” (p < 0.004). These data support the importance of alexithymia as a non-motor symptom in PD. MDPI 2020-06-24 /pmc/articles/PMC7348697/ /pubmed/32599704 http://dx.doi.org/10.3390/brainsci10060401 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Klietz, Martin
Schnur, Theresa
Drexel, Simon C.
Lange, Florian
Paracka, Lejla
Huber, Meret K.
Dressler, Dirk
Höglinger, Günter U.
Wegner, Florian
Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title_full Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title_fullStr Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title_full_unstemmed Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title_short Alexithymia Is Associated with Reduced Quality of Life and Increased Caregiver Burden in Parkinson’s Disease
title_sort alexithymia is associated with reduced quality of life and increased caregiver burden in parkinson’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348697/
https://www.ncbi.nlm.nih.gov/pubmed/32599704
http://dx.doi.org/10.3390/brainsci10060401
work_keys_str_mv AT klietzmartin alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT schnurtheresa alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT drexelsimonc alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT langeflorian alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT parackalejla alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT hubermeretk alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT dresslerdirk alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT hoglingergunteru alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease
AT wegnerflorian alexithymiaisassociatedwithreducedqualityoflifeandincreasedcaregiverburdeninparkinsonsdisease