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Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes

Astrocytes, the most numerous cells of the central nervous system, exert critical functions for brain homeostasis. To this purpose, astrocytes generate a highly interconnected intercellular network allowing rapid exchange of ions and metabolites through gap junctions, adjoined channels composed of h...

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Detalles Bibliográficos
Autores principales: Lanciotti, Angela, Brignone, Maria Stefania, Belfiore, Marcello, Columba-Cabezas, Sandra, Mallozzi, Cinzia, Vincentini, Olimpia, Molinari, Paola, Petrucci, Tamara Corinna, Visentin, Sergio, Ambrosini, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348769/
https://www.ncbi.nlm.nih.gov/pubmed/32521795
http://dx.doi.org/10.3390/cells9061425