Cargando…

Unusual mtDNA Control Region Length Heteroplasmy in the COS-7 Cell Line

The COS-7 cell line is a workhorse of virology research. To expand this cell line’s utility and to enable studies on mitochondrial DNA (mtDNA) transcription and replication, we determined the complete nucleotide sequence of its mitochondrial genome by Sanger sequencing. In contrast to other availabl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kozhukhar, Nataliya, Mitta, Sunil, Alexeyev, Mikhail F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348793/ https://www.ncbi.nlm.nih.gov/pubmed/32486194 http://dx.doi.org/10.3390/genes11060607

Ejemplares similares

TFAM’s Contributions to mtDNA Replication and OXPHOS Biogenesis Are Genetically Separable
por: Kozhukhar, Natalya, et al.
Publicado: (2022)

Presequence-Independent Mitochondrial Import of DNA Ligase Facilitates Establishment of Cell Lines with Reduced mtDNA Copy Number
por: Spadafora, Domenico, et al.
Publicado: (2016)

Correction: Presequence-Independent Mitochondrial Import of DNA Ligase Facilitates Establishment of Cell Lines with Reduced mtDNA Copy Number
por: Spadafora, Domenico, et al.
Publicado: (2016)

A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions
por: Fayzulin, Rafik Z., et al.
Publicado: (2015)

A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication
por: Kozhukhar, Natalya, et al.
Publicado: (2022)

Evaluating sequence-derived mtDNA length heteroplasmy by amplicon size analysis
por: Berger, C., et al.
Publicado: (2011)

TFAM in mtDNA Homeostasis: Open Questions
por: Alexeyev, Mikhail
Publicado: (2023)

Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy
por: Latorre-Pellicer, Ana, et al.
Publicado: (2019)

Single-cell individual full-length mtDNA sequencing by iMiGseq uncovers unexpected heteroplasmy shifts in mtDNA editing
por: Bi, Chongwei, et al.
Publicado: (2023)

Paternal leakage and mtDNA heteroplasmy in Rhipicephalus spp. ticks
por: Mastrantonio, Valentina, et al.
Publicado: (2019)

mtDNA Heteroplasmy: Origin, Detection, Significance, and Evolutionary Consequences
por: Parakatselaki, Maria-Eleni, et al.
Publicado: (2021)

The mitochondrial genome sequence of the BS-C-1 cell line is at odds with the reported derivation from Cercopithecus aethiops
por: Kozhukhar, Nataliya, et al.
Publicado: (2020)

Nuclear genetic control of mtDNA copy number and heteroplasmy in humans
por: Gupta, Rahul, et al.
Publicado: (2023)

Nuclear genetic control of mtDNA copy number and heteroplasmy in humans
por: Gupta, Rahul, et al.
Publicado: (2023)

Variation in germ line mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission
por: Freyer, Christoph, et al.
Publicado: (2012)

No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline
por: Hagström, Erik, et al.
Publicado: (2014)

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA
por: Jayaprakash, Anitha D., et al.
Publicado: (2015)

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number
por: Wachsmuth, Manja, et al.
Publicado: (2016)

Transmission from centenarians to their offspring of mtDNA heteroplasmy revealed by ultra-deep sequencing
por: Giuliani, Cristina, et al.
Publicado: (2014)

Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome
por: Hübner, Alexander, et al.
Publicado: (2019)

Distant hybrids of Heliocidaris crassispina (♀) and Strongylocentrotus intermedius (♂): identification and mtDNA heteroplasmy analysis
por: Zhan, Yaoyao, et al.
Publicado: (2020)

Analyzing Low-Level mtDNA Heteroplasmy—Pitfalls and Challenges from Bench to Benchmarking
por: Fazzini, Federica, et al.
Publicado: (2021)

Segregation of point mutation heteroplasmy in the control region of dog mtDNA studied systematically in deep generation pedigrees
por: Klütsch, Cornelya F. C., et al.
Publicado: (2010)

Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy
por: Holland, Mitchell M., et al.
Publicado: (2011)

Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection
por: Barker, Peter E., et al.
Publicado: (2009)

High incidence of heteroplasmy in the mtDNA of a natural population of the spider crab Maja brachydactyla
por: Rodríguez-Pena, Elba, et al.
Publicado: (2020)

Ancient hybridization and mtDNA introgression behind current paternal leakage and heteroplasmy in hybrid zones
por: Mastrantonio, Valentina, et al.
Publicado: (2019)

Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection
por: Giannakis, Konstantinos, et al.
Publicado: (2023)

Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck
por: Li, Mingkun, et al.
Publicado: (2016)

LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria
por: Yang, Qiyuan, et al.
Publicado: (2022)

Tissue-specific heteroplasmy segregation is accompanied by a sharp mtDNA decline in Caenorhabditis elegans soma
por: Tsyba, Nikita, et al.
Publicado: (2023)

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease
por: Bacman, Sandra R., et al.
Publicado: (2010)

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease
por: Nicholls, Thomas J., et al.
Publicado: (2014)

Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations
por: Burgstaller, Joerg P., et al.
Publicado: (2018)

mtDNA heteroplasmy level and copy number indicate disease burden in m.3243A>G mitochondrial disease
por: Grady, John P, et al.
Publicado: (2018)

mtDNA heteroplasmy gives rise to a new maternal lineage in North Pacific humpback whales (Megaptera novaeangliae)
por: Pierszalowski, Sophie P, et al.
Publicado: (2022)

A Twin Study of Mitochondrial DNA Polymorphisms Shows that Heteroplasmy at Multiple Sites Is Associated with mtDNA Variant 16093 but Not with Zygosity
por: Andrew, Toby, et al.
Publicado: (2011)

Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner
por: Loutre, Romuald, et al.
Publicado: (2018)

The C-Terminal Tail of Mitochondrial Transcription Factor A Is Dispensable for Mitochondrial DNA Replication and Transcription In Situ
por: Kozhukhar, Natalya, et al.
Publicado: (2023)

Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication
por: Suissa, Sarit, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_97gmiuqaf4of14uq705se601uc