Cargando…

Adenosine A(2A)Receptors in Substance Use Disorders: A Focus on Cocaine

Several psychoactive drugs can evoke substance use disorders (SUD) in humans and animals, and these include psychostimulants, opioids, cannabinoids (CB), nicotine, and alcohol. The etiology, mechanistic processes, and the therapeutic options to deal with SUD are not well understood. The common featu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wydra, Karolina, Gawliński, Dawid, Gawlińska, Kinga, Frankowska, Małgorzata, Borroto-Escuela, Dasiel O., Fuxe, Kjell, Filip, Małgorzata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348840/ https://www.ncbi.nlm.nih.gov/pubmed/32492952 http://dx.doi.org/10.3390/cells9061372

Ejemplares similares

On the role of A(2A) and D(2) receptors in control of cocaine and food-seeking behaviors in rats
por: Wydra, Karolina, et al.
Publicado: (2014)

A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Cocaine and Its Abstinence Condition Modulate Striatal and Hippocampal Wnt Signaling in a Male Rat Model of Drug Self-Administration
por: Gawliński, Dawid, et al.
Publicado: (2022)

Maternal Diet Influences the Reinstatement of Cocaine-Seeking Behavior and the Expression of Melanocortin-4 Receptors in Female Offspring of Rats
por: Gawliński, Dawid, et al.
Publicado: (2020)

Cocaine Administration and Its Abstinence Conditions Modulate Neuroglia
por: Gawlińska, Kinga, et al.
Publicado: (2020)

OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Effects of intra-accumbal or intra-prefrontal cortex microinjections of adenosine 2A receptor ligands on responses to cocaine reward and seeking in rats
por: Wydra, K., et al.
Publicado: (2018)

Disruption of A2AR-D2R Heteroreceptor Complexes After A2AR Transmembrane 5 Peptide Administration Enhances Cocaine Self-Administration in Rats
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocytes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2023)

The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2021)

Adenosine heteroreceptor complexes in the basal ganglia are implicated in Parkinson’s disease and its treatment
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Acute Cocaine Enhances Dopamine D(2)R Recognition and Signaling and Counteracts D(2)R Internalization in Sigma1R-D(2)R Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

The coming together of allosteric and phosphorylation mechanisms in the molecular integration of A2A heteroreceptor complexes in the dorsal and ventral striatal-pallidal GABA neurons
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2021)

Understanding the Functional Plasticity in Neural Networks of the Basal Ganglia in Cocaine Use Disorder: A Role for Allosteric Receptor-Receptor Interactions in A2A-D2 Heteroreceptor Complexes
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2016)

Molecular Integration in Adenosine Heteroreceptor Complexes Through Allosteric and De-Phosphorylation (STEP) Mechanisms and its Role in Brain Disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2022)

Maternal feeding patterns affect the offspring’s brain: focus on serotonin 5-HT(2C) and 5-HT(2A) receptors
por: Gawlińska, Kinga, et al.
Publicado: (2021)

The effects of cocaine exposure in adolescence: Behavioural effects and neuroplastic mechanisms in experimental models
por: Caffino, Lucia, et al.
Publicado: (2021)

Maternal dietary patterns are associated with susceptibility to a depressive-like phenotype in rat offspring
por: Gawlińska, Kinga, et al.
Publicado: (2020)

Can Allosteric Receptor-Protein Interactions in Receptor Complexes Be a Molecular Mechanism Involved in Cancer Immune Therapy?
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Oligomeric Receptor Complexes and Their Allosteric Receptor-Receptor Interactions in the Plasma Membrane Represent a New Biological Principle for Integration of Signals in the CNS
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

Volume transmission and receptor-receptor interactions in heteroreceptor complexes: understanding the role of new concepts for brain communication
por: Fuxe, Kjell, et al.
Publicado: (2016)

On the G Protein-Coupled Receptor Neuromodulation of the Claustrum
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2019)

The integrative role of G protein-coupled receptor heterocomplexes in Parkinson’s disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2022)

Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

A Maternal High-Fat Diet during Early Development Provokes Molecular Changes Related to Autism Spectrum Disorder in the Rat Offspring Brain
por: Gawlińska, Kinga, et al.
Publicado: (2021)

Evidence for the existence of dopamine D2R and Sigma 1 allosteric receptor-receptor interaction in the rat brain: role in brain plasticity and cocaine action
por: Pinton, Luca, et al.
Publicado: (2015)

Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2020)

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?
por: Beggiato, Sarah, et al.
Publicado: (2021)

Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring
por: Gawlińska, Kinga, et al.
Publicado: (2021)

Potential of caveolae in the therapy of cardiovascular and neurological diseases
por: Navarro, Gemma, et al.
Publicado: (2014)

Mapping the Interface of a GPCR Dimer: A Structural Model of the A(2A) Adenosine and D(2) Dopamine Receptor Heteromer
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2018)

Cocaine Self-Administration and Abstinence Modulate NMDA Receptor Subunits and Active Zone Proteins in the Rat Nucleus Accumbens
por: Smaga, Irena, et al.
Publicado: (2020)

IL1R2, CCR2, and CXCR4 May Form Heteroreceptor Complexes with NMDAR and D2R: Relevance for Schizophrenia
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

Diversity and Bias through Receptor–Receptor Interactions in GPCR Heteroreceptor Complexes. Focus on Examples from Dopamine D2 Receptor Heteromerization
por: Fuxe, Kjell, et al.
Publicado: (2014)

Prolonged Induction of miR-212/132 and REST Expression in Rat Striatum Following Cocaine Self-Administration
por: Sadakierska-Chudy, Anna, et al.
Publicado: (2016)

Novel GPR18 Ligands in Rodent Pharmacological Tests: Effects on Mood, Pain, and Eating Disorders
por: Frankowska, Małgorzata, et al.
Publicado: (2023)

A High-Sugar Diet Consumption, Metabolism and Health Impacts with a Focus on the Development of Substance Use Disorder: A Narrative Review
por: Witek, Kacper, et al.
Publicado: (2022)

Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease
por: Borroto-Escuela, Dasiel O., et al.
Publicado: (2017)

Cocaine Administration and Its Withdrawal Enhance the Expression of Genes Encoding Histone-Modifying Enzymes and Histone Acetylation in the Rat Prefrontal Cortex
por: Sadakierska-Chudy, Anna, et al.
Publicado: (2017)

Maternal High-Fat Diet Modulates Cnr1 Gene Expression in Male Rat Offspring
por: Gawliński, Dawid, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_iphvh0luekag2qgvuo25okqnjm