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An Update on the Molecular Basis of Phosphoantigen Recognition by Vγ9Vδ2 T Cells

About 1–5% of human blood T cells are Vγ9Vδ2 T cells. Their hallmark is the expression of T cell antigen receptors (TCR) whose γ-chains contain a rearrangement of Vγ9 with JP (TRGV9JP or Vγ2Jγ1.2) and are paired with Vδ2 (TRDV2)-containing δ-chains. These TCRs respond to phosphoantigens (PAg) such a...

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Detalles Bibliográficos
Autores principales:	Herrmann, Thomas, Fichtner, Alina Suzann, Karunakaran, Mohindar Murugesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348870/ https://www.ncbi.nlm.nih.gov/pubmed/32527033 http://dx.doi.org/10.3390/cells9061433

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