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Protective Effects of SIRT6 Overexpression against DSS-Induced Colitis in Mice

Sirtuin 6 (SIRT6), as a NAD + -dependent deacetylase, plays an indispensable role in the regulation of health and physiology. Loss of SIRT6 causes spontaneous colitis in mice and makes intestinal epithelial cells prone to stress. However, whether SIRT6 overexpression increases resistance to colitis...

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Detalles Bibliográficos
Autores principales:	Xu, Kang, Guo, Yannan, Ping, Lu, Qiu, Ying, Liu, Qingfei, Li, Zhongchi, Wang, Zhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348883/ https://www.ncbi.nlm.nih.gov/pubmed/32580272 http://dx.doi.org/10.3390/cells9061513

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