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Overlap of Peak Growth Activity and Peak IGF-1 to IGFBP Ratio: Delayed Increase of IGFBPs Versus IGF-1 in Serum as a Mechanism to Speed up and down Postnatal Weight Gain in Mice

Forced expression of insulin-like growth factor binding proteins (IGFBPs) in transgenic mice has clearly revealed inhibitory effects on somatic growth. However, by this approach, it cannot be solved if or how IGFBPs rule insulin-like growth factor (IGF)-dependent growth under normal conditions. In o...

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Detalles Bibliográficos
Autores principales:	Walz, Michael, Chau, Luong, Walz, Christina, Sawitzky, Mandy, Ohde, Daniela, Brenmoehl, Julia, Tuchscherer, Armin, Langhammer, Martina, Metzger, Friedrich, Höflich, Christine, Hoeflich, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348928/ https://www.ncbi.nlm.nih.gov/pubmed/32580353 http://dx.doi.org/10.3390/cells9061516

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