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High Throughput strategies Aimed at Closing the GAP in Our Knowledge of Rho GTPase Signaling

Since their discovery, Rho GTPases have emerged as key regulators of cytoskeletal dynamics. In humans, there are 20 Rho GTPases and more than 150 regulators that belong to the RhoGEF, RhoGAP, and RhoGDI families. Throughout development, Rho GTPases choregraph a plethora of cellular processes essenti...

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Detalles Bibliográficos
Autores principales: Dahmene, Manel, Quirion, Laura, Laurin, Mélanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348934/
https://www.ncbi.nlm.nih.gov/pubmed/32526908
http://dx.doi.org/10.3390/cells9061430