Cargando…

Immunization with Human Cytomegalovirus Core Fusion Machinery and Accessory Envelope Proteins Elicit Strong Synergistic Neutralizing Activities

Human cytomegalovirus (HCMV) core fusion machinery proteins gB and gH/gL, and accessory proteins UL128/UL130/UL131A, are the key envelope proteins that mediate HCMV entry into and infection of host cells. To determine whether these HCMV envelope proteins could elicit neutralizing activities synergis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Xinle, Cao, Zhouhong, Wang, Shuishu, Adler, Stuart P., McVoy, Michael A., Snapper, Clifford M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348949/ https://www.ncbi.nlm.nih.gov/pubmed/32294946 http://dx.doi.org/10.3390/vaccines8020179

Ejemplares similares

Immunization of Rabbits with Recombinant Human Cytomegalovirus Trimeric versus Monomeric gH/gL Protein Elicits Markedly Higher Titers of Antibody and Neutralization Activity
por: Cui, Xinle, et al.
Publicado: (2019)

Immunization with Epstein–Barr Virus Core Fusion Machinery Envelope Proteins Elicit High Titers of Neutralizing Activities and Protect Humanized Mice from Lethal Dose EBV Challenge
por: Cui, Xinle, et al.
Publicado: (2021)

Development of novel vaccines against human cytomegalovirus
por: Cui, Xinle, et al.
Publicado: (2019)

Intravaginal cytomegalovirus (CMV) challenge elicits maternal viremia and results in congenital transmission in a guinea pig model
por: Olejniczak, Megan J, et al.
Publicado: (2011)

Bacterial Artificial Chromosome Clones of Viruses Comprising the Towne Cytomegalovirus Vaccine
por: Cui, Xiaohong, et al.
Publicado: (2012)

The RL13 Temperance Factor Represses Replication of the Highly Cell Culture-Adapted Towne Strain of Human Cytomegalovirus
por: Ourahmane, Amine, et al.
Publicado: (2023)

Changes in subcellular localization reveal interactions between human cytomegalovirus terminase subunits
por: Wang, Jian Ben, et al.
Publicado: (2012)

Cytomegalovirus Strain TB40/E Restrictions and Adaptations to Growth in ARPE-19 Epithelial Cells
por: Vo, Mai, et al.
Publicado: (2020)

Comparative neutralizing potencies of antibodies suggest conservation as well as mechanistic differences in human cytomegalovirus entry into epithelial and endothelial cells
por: Qi, Ying, et al.
Publicado: (2020)

Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases
por: Cui, Xinle, et al.
Publicado: (2021)

Genome Sequence of Human Cytomegalovirus Ig-KG-H2, a Variant of Strain KG Propagated in the Presence of Neutralizing Antibodies
por: Al Qaffas, Ahmed, et al.
Publicado: (2020)

Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination
por: Li, Fengsheng, et al.
Publicado: (2017)

Polymorphic Forms of Human Cytomegalovirus Glycoprotein O Protect against Neutralization of Fibroblast Entry by Antibodies Targeting Epitopes Defined by Glycoproteins H and L
por: He, Li, et al.
Publicado: (2022)

Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
por: Schleiss, Mark R, et al.
Publicado: (2008)

Human Cytomegalovirus Replication and Infection-Induced Syncytia Formation in Labial, Foreskin, and Fetal Lung Fibroblasts
por: Aguiar, Alexis, et al.
Publicado: (2021)

Single-Cell Transcriptome Analysis of CD34(+) Stem Cell-Derived Myeloid Cells Infected With Human Cytomegalovirus
por: Galinato, Melissa, et al.
Publicado: (2019)

Human cytomegalovirus hijacks the autophagic machinery and LC3 homologs in order to optimize cytoplasmic envelopment of mature infectious particles
por: Taisne, Clémence, et al.
Publicado: (2019)

Anti-cytomegalovirus activity of the anthraquinone atanyl blue PRL
por: Alam, Zohaib, et al.
Publicado: (2015)

Complete Genome Sequence of Pathogenic Guinea Pig Cytomegalovirus from Salivary Gland Homogenates of Infected Animals
por: Yang, Dongmei, et al.
Publicado: (2013)

Comprehensive Analysis of Human Cytomegalovirus MicroRNA Expression during Lytic and Quiescent Infection
por: Shen, Zhang-Zhou, et al.
Publicado: (2014)

Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting
por: Cheng, Cheng, et al.
Publicado: (2019)

Correction: Comprehensive Analysis of Human Cytomegalovirus MicroRNA Expression during Lytic and Quiescent Infection
por: Shen, Zhang-Zhou, et al.
Publicado: (2020)

Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex
por: Ha, Sha, et al.
Publicado: (2017)

Complete Genome Sequence of Cell Culture-Attenuated Guinea Pig Cytomegalovirus Cloned as an Infectious Bacterial Artificial Chromosome
por: Yang, Dongmei, et al.
Publicado: (2014)

Genome Sequences of Diverse Human Cytomegalovirus Strains with Utility in Drug Screening and Vaccine Evaluation
por: Corcoran, Kathleen, et al.
Publicado: (2017)

Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells
por: Al Qaffas, Ahmed, et al.
Publicado: (2021)

Molecular and Biological Characterization of a New Isolate of Guinea Pig Cytomegalovirus
por: Schleiss, Mark R., et al.
Publicado: (2014)

HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide
por: Wang, Shuishu, et al.
Publicado: (2023)

Impairment in Neurocognitive Function Following Experimental Neonatal Guinea Pig Cytomegalovirus Infection
por: Fernández-Alarcón, Claudia, et al.
Publicado: (2020)

HIV-1 envelope trimer elicits higher neutralizing antibody responses than monomeric gp120
por: Kovacs, JM, et al.
Publicado: (2012)

Inclusion of the Guinea Pig Cytomegalovirus Pentameric Complex in a Live Virus Vaccine Aids Efficacy against Congenital Infection but Is Not Essential for Improving Maternal and Neonatal Outcomes
por: Schleiss, Mark R., et al.
Publicado: (2021)

Principal-axis transformation for a free nucleon coupled to an uncharged scalar meson field
por: McVoy, Kirk W, et al.
Publicado: (1956)

Dendritic Cells Pulsed with Intact Streptococcus pneumoniae Elicit both Protein- and Polysaccharide-specific Immunoglobulin Isotype Responses In Vivo through Distinct Mechanisms
por: Colino, Jesus, et al.
Publicado: (2002)

Arms Race between Enveloped Viruses and the Host ERAD Machinery
por: Frabutt, Dylan A., et al.
Publicado: (2016)

Filamentous structures in the cell envelope are associated with bacteroidetes gliding machinery
por: Shibata, Satoshi, et al.
Publicado: (2023)

Immunization with HIV-1 envelope T20-encoding DNA vaccines elicits cross-clade neutralizing antibody responses
por: Stenler, S., et al.
Publicado: (2017)

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response
por: Tzeng, Stephany Y., et al.
Publicado: (2018)

Theoretical Methods in Medium-Energy and Feavy-Ion Physics
por: Friedman, William Albert, et al.
Publicado: (1978)

Does the ground-state resonance of $^{10}$Li overlap neutron threshold?
por: McVoy, Kirk W, et al.
Publicado: (1994)

Evaluation of the Relationship of Sleep Disturbances to Severity and Common Behaviors in Autism Spectrum Disorder
por: Miner, Stacy, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s16d0t4msql5bgbpiibprepi2v