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Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

messenger RNA (mRNA)-based vaccines combine the positive attributes of both live-attenuated and subunit vaccines. In order for these to be applied for clinical use, they require to be formulated with delivery systems. However, there are limited in vivo studies which compare different delivery platfo...

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Detalles Bibliográficos
Autores principales: Anderluzzi, Giulia, Lou, Gustavo, Gallorini, Simona, Brazzoli, Michela, Johnson, Russell, O’Hagan, Derek T., Baudner, Barbara C., Perrie, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7348957/
https://www.ncbi.nlm.nih.gov/pubmed/32397231
http://dx.doi.org/10.3390/vaccines8020212