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Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart

The Alternative Reading Frame (ARF) protein is a tumor suppressor encoded by the Cyclin Dependent Kinase Inhibitor 2A gene in mammals but not lower regenerative vertebrates, and has been previously implicated as a context-sensitive suppressor of regeneration in murine skeletal muscle and humanized A...

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Detalles Bibliográficos
Autores principales: Lee, Solomon, Hesse, Robert, Tamaki, Stanley, Garland, Catharine, Pomerantz, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349231/
https://www.ncbi.nlm.nih.gov/pubmed/32570883
http://dx.doi.org/10.3390/genes11060666