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IL-6 trans-Signaling Impairs Sprouting Angiogenesis by Inhibiting Migration, Proliferation and Tube Formation of Human Endothelial Cells

Sprouting angiogenesis is the formation of new capillaries from existing vessels in response to tissue hypoxia due to growth/development, repair/healing, and also chronic inflammation. In this study, we aimed to elucidate the effect of IL-6, a pleiotropic cytokine with both pro-inflammatory and anti...

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Detalles Bibliográficos
Autores principales: Zegeye, Mulugeta M, Andersson, Blanka, Sirsjö, Allan, Ljungberg, Liza U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349366/
https://www.ncbi.nlm.nih.gov/pubmed/32517159
http://dx.doi.org/10.3390/cells9061414