A Dual Face of APE1 in the Maintenance of Genetic Stability in Monocytes: An Overview of the Current Status and Future Perspectives

Monocytes, which play a crucial role in the immune system, are characterized by an enormous sensitivity to oxidative stress. As they lack four key proteins responsible for DNA damage response (DDR) pathways, they are especially prone to reactive oxygen species (ROS) exposure leading to oxidative DNA...

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Detalles Bibliográficos
Autores principales: Betlej, Gabriela, Bator, Ewelina, Pyrkosz, Antoni, Kwiatkowska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349382/
https://www.ncbi.nlm.nih.gov/pubmed/32545201
http://dx.doi.org/10.3390/genes11060643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349382/
https://www.ncbi.nlm.nih.gov/pubmed/32545201
http://dx.doi.org/10.3390/genes11060643

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